Authors:
Belgi Diren Sigirci, Oktay Ozkan
, Kemal Metiner
, Beren Basaran Kahraman
, Baran Celik
, Seyyal Ak ,Turkey
|
Abstract:
The development of antibiotic resistance has been required to discover the new antimicrobial
agents mainly among plant extracts. In this study, the antibacterial and antifungal properties of
Taraxacum officinale were investigated. The antibacterial activity of the extract was examined
by agar dilution method and determined the minimum inhibitory concentration (MIC) value
according to clinical and laboratory standards institute (formerly CLSI). The antifungal effect of
the extract was examined with the broth macrodilution method according to CLSI. Ethanolic
extract of Taraxacumofficinaleleaves described the highest activity against B. cereus (15.25
mg/ml) and B.subtilis (61 mg/ml) while it showed the lowest activity against E.coli, S.enteritidis,
P. aeruginosa, S. aureus,S. Epidermidis and E.faecalis(122 mg/ml). The extracts were found to
be effective against all strains of the fungal used but only in high concentrations. Extract
demonstrated the highest effectiveness against C. albicans and M. nanum (610 mg/ml) although
it indicated the lowest effectiveness against C. krusei, C. parapsilosis, M. pachydermatis, M.
canis, M. gypseum and T. mentagrophytes (1220 mg/ml). As a conclusion, Taraxacum
officinalecanbe exploited in the management of pathogenic bacteria and fungi to develop an
alternative therapy. |
