Antifungal effects of aqueous extracts of Hyptis suaveolens (Pignut), Khaya grandifoliola (large leave khaya), Zingiber officinale (Ginger), Calophyllum inophyllum (Mast wood) and Datura stramonium (Jimson weed), on the radial growth of fungal pathogens of pineapple fruit was investigated, varied concentrations of extracts from the different plant parts were tested against the rot organisms, the highest aqueous extract inhibitory effect of Zingiber officinale was on Aspergillus nidulans (26.00%) at 1.0g/mL while the least inhibitory effect was on Colletotrichum fruticola (22.00% ) at 1.0g/mL, the highest aqueous extract inhibition of Datura stramonium was on Aspergillus niger (14.00%) at 1.0g/mL while the least inhibitory effect was (0.00%) on Aspergillus flavus and Colletotrichum fruticola at all concentrations, the highest aqueous extract inhibition of Calophyllum inophyllum was (15.00%) on Aspergillus fumigatus and Aspergillus nidulans at 1.0g/mL while the least inhibitory effect was 12.00% on Aspergillus tubingensis at 1.0g/mL, the highest aqueous extract inhibition of Hyptis suaveolens was 18.00% on Trichoderma harzianum and Aspergillus fumigatus at 1.0g/mL while the least inhibitory effect was 10.00% on Aspergillus niger at 1.0g/mL, the highest aqueous extract inhibition of Khaya grandifoliola was 18.00% on Aspergillus flavus at 1.00g/mL while the least inhibitory effect was 10.00% on Aspergillus niger at 1.0g/mL, the fungitoxic potential of these plant extracts on rot inducing fungi of pineapple fruit is an indication of their use by farmers as alternative to commercial or synthetic fungicide that pose danger to our ecosystem and health. The effects of rot organisms on the proximate composition of the fruit were not significant on the nutrient level of the fruit.