Authors:
Jamila Khribch, Smara Naima
, Laghrib Farida
, S.Nassik, S.ZRIRA
, M. EL HOUADFI
, M. Oukessou |
Abstract:
The development of bacterial resistance to common antimicrobial agents is a major challenge for
actors in the field of human and animal health. This has prompted the search for new
antimicrobial agents from a variety of sources, including plants. The present study investigates
the antibacterial activity of cinnamon essential oil and its major constituent, the cinnamaldehyde.
This activity was evaluated using standard aromatogram technique and the liquid macrodilution
technique for MIC and MBC determination using a reference germ test (E. coli ATCC25922)
and forty antibiotic resistant E. coli strains isolated from broiler chickens. In a second part of the
study, cinnamaldehyde was combined to certain antibiotics and tested for possible synergies. The
obtained results have showed, cinnamon essential oil was more active than cinnamaldehyde. The
average MIC values obtained with cinnamaldehyde were 0.031% and 0.04% for reference and
avian E. coli respectively, and the average MBC value was 0.031% for the reference strain. The
bactericidal activity of Cinnamaldehyde against E. coli is close to the time-dependent kind
antibiotics against E. coli bacteria. Combinations of Cinnamaldehyde-antibiotics were indifferent
against the reference E. coli strain.
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