Pekmezs (molasses) are produced traditional or fabrication of different flavor, structure and appearance in Turkey. Pekmez composition and structure vary according to fruit and production process. Pekmezs are classified two main groups as liquid and solid pekmez. There are also different classifications. Pekmezs are especially rich in carbohydrates and minerals, also pekmezs contain vitamins, antioxidants and flavonoids. Pekmez is an energy store and food source. It is also consumed for protective or therapeutic purposes due to its contribution to human health. Pekmezs can affect positively many diseases such as diabetes, diarrhea, liver, kidney, stomach, intestine, lung, mouth and throat diseases, flu, cough, asthma, bronchitis, jaundice, measles, reflux, vascular occlusion, angina, cholesterol and anemia. In this review, information was given about the effects of pekmez produced in Turkey on the production, composition and human health.